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      This conference will be held to celebrate the 150th birthday 
        of Paul Ehrlich, who made a Nobel Prize Laureate in 1908. He was probably 
        one of the most ingenious and visionary pharmacologists of the last century. 
        The work of Paul Ehrlich led to the first antibiotic ever developed by 
        systematic research. The anti-syphilitic agent called Salvarsan® (Arsphenamine, 
        "compound 606") confronted great challenges to its appropriate 
        dosing, challenges that Ehrlich met with brilliant published fundamental 
        work that still applies. He would certainly have been honored by this 
        conference. We will remember Paul Ehrlich in many ways in our scientific 
        and celebration program. The 
        conference will be under the auspices of the International Society of 
        Chemotherapy and other German and international societies dedicated to 
        the work of Paul Ehrlich. 
      Dosing the magic bullets - clinicians meet pharmacologists 
        There is no doubt that dosing of anti-infectives 
        is still a major issue in the use of these agents. Recently the dosing 
        aspect has very much been directed to optimization of antibiotic therapy 
        and resistance issues by applying the new pharmacokinetic (PK)/pharmacodynamic 
        (PD) principles. In previous decades, dosing issues and drug monitoring 
        were more related to predicting adverse events. No conference has yet 
        focused exclusively on dosing by applying the new PK/PD principles that 
        have led to many new insights. This conference gathers the leaders in 
        this field of PK/PD and clinical medicine to exchange views. The PK/PD 
        group will review the concepts and the clinicians will show which principles 
        have been acknowledged and introduced into antimicrobial therapy. Active 
        participation of the attendees in this conference is assured by using 
        modern technology. Use this excellent opportunity of clinicians meeting 
        pharmacologists 
      Discuss and evaluate dosing guidelines 
        Use of antiinfectives and dosing guidelines from scientific organizations, 
        hospitals or other groups are cordially invited to participate in the 
        conference. During the whole conference a "Guidelines' Corner" 
        will allow discussion of guidelines from around the globe - WORLD CONFERENCE! 
        Make yourself heard by submitting a poster on your guidelines and participate 
        in the "Ehrlich-Magic-Bullet"-Award (see poster 
        abstract and poster guidelines 
        for details). 
      Pre-conference workshops 
        The new principles of PK/PD offer fascinating opportunities to optimize 
        anti-infective therapy. At the conference, participants have two consecutive 
        options to study PK/PD and dosing issues. At the post-graduate workshop 
        from Monday to Wednesday, leading experts in PK/PD from the International 
        Society of Antiinfective Pharmacology will lead teaching courses in this 
        field (see program). Everything will be truly hands-on - with a computer, 
        the right software and true data sets from the 'real world'. There will 
        also be a bioanalytical component with chromatography, mass spectrometry, 
        microdialysis, protein binding and tissue level determination planned. 
        See how the professionals do this. The whole week can truly be a week 
        of Ehrlich excellence. Ehrlich in German also means 'true', 'honest' and 
        'sincere'. 
      Conference logo 
        The logo shows the three major steps to Ehrlich's magic bullets: methylene 
        blue to fight malaria (1891), trypan red against trypanosomes (1904), 
        yellow - the color of 'Compound 606' (Salvarsan), the first antibiotic 
        and truly Ehrlich's MAGIC BULLET (1910) against syphilis.  
      Poster presentations 
        We invite poster submissions of new and original data. Interesting case 
        reports and opinion papers that stimulate discussion are also welcomed. 
        Make yourself heard on a controversial issue or present a new laboratory 
        method, new calculation methods or simply something you want to have discussed 
        in a stimulating environment.  
      Conference language 
        English. 
      Communication between participants 
        In the spirit of Paul Ehrlich, special areas will be assigned for attendees 
        from around the world to meet and exchange ideas. The conference site 
        will also be decorated to honor Paul Ehrlich´s work and achievements. 
        Paul Ehrlich loved colors; as a scientist he used dyes to fight against 
        infectious agents and as an artist he liked to play with colors in his 
        laboratory notebooks or sketches that he prepared wherever he had to explain 
        his ingenious 'colorful' theories. The young artists who created their 
        Ehrlich-inspired artwork will be on hand to discuss their work. Ehrlich's 
        work will also be celebrated in a specially written play which will be 
        performed during the gala evening. This conference is held in the city 
        of the famous artist, Albrecht Dürer, where we will invite young 
        artists to use the Ehrlich colors to decorate and enlighten this unique 
        conference. 
       The conference venue 
        Nürnberg is one of Germany's most enchanting cities. In 1424 Nürnberg 
        was designated as the location for the safekeeping of the imperial jewels 
        and the imperial relics. The Free Imperial City was at its zenith and 
        was often called the 'capital of the Middle Ages'. This European metropolis 
        developed into a centre of German humanistic sciences, arts and sculpture. 
        Martin Behaim designed the first globe while Hans Sachs and the poetry 
        of the Meistersingers made the city one of world renown. The wood carver 
        Veit Stoß and the sculptor Adam Kraft created works of art of the 
        highest European level, while Albrecht Dürer, one of the Renaissance's 
        greatest painters, was born in Nürnberg. After a dark episode in 
        the last century, in recent years the city has gained a reputation for 
        its annual international human rights prize. Nürnberg is a flourishing 
        and thoroughly modern city. It is sure to provide the best possible welcome 
        to the scientists and historians from around the world.  
      Gala evening celebrating Paul 
        Ehrlich 
        Do not miss this great event to celebrate Paul Ehrlich. Highlights include: 
           1. A play celebrating Paul Ehrlich that has been written 
        exclusively for the conference  
           2. Listen to the recollections of someone who knew Paul 
        Ehrlich personally  
           3. A 'magic gift' for all participants of the scientific 
        conference  
      THE HISTORY AND CELEBRATION 
        PAUL EHRLICH BIOGRAPHY WORKSHOP, EXHIBITION AND PLAY 
        Learn more about this great scientist's visionary abilities and lifetime 
        achievements  
      
        - Attend the first-ever historians' and chemotherapy 
          researchers' conference on Paul Ehrlich.
 
        -  View previously unseen exhibits of Paul Ehrlich
 
        - See artists using Ehrlich's colors; Ehrlich loved 
          to use and play with colors - in the laboratory and elsewhere 
 
        -  Join a great celebration dinner on Friday, September 
          10, 2004, with the première of a play celebrating Paul Ehrlich 
          that has been written exclusively for this conference
 
        -  Receive your unique 'Magic Gift', which you can only 
          receive on the gala evening, and has never been given before
 
       
      Conveners 
        - Fritz Sörgel, Nürnberg-Heroldsberg, Germany (Chairman), 
        - George L Drusano, Albany, NY, USA (Co Chairman), 
        - Dieter Adam, Munich, Germany (Honorary Secretary), 
        - Kurt G Naber, Straubing, Germany (Honorary Treasurer), 
        - Klaus-Friedrich Bodmann, Hildesheim, Germany (Satellite Symposia Coordinator). 
         
        E-Mail Address of Conference 
        mail@ehrlich2004.org (please 
        use this address exclusively) 
      Address for correspondence and 
        enquiries 
        Whenever during the preparation of this conference in the months ahead 
        or during the conference you have a special need or need help, please 
        feel free to contact me at any time: 
      Professor Fritz Sörgel 
        Institute for Biomedical and 
        Pharmaceutical Research, 
        Paul-Ehrlich-Strasse 19, 
        90562 Nürnberg - Heroldsberg, 
        Germany 
        Tel: +49 911 518 290 
        Fax: +49 911 518 2920 
        E-mail: ibmp@osn.de 
      
      Register 
        early to qualify for the following great offers 
      
        -  A "Week of Ehrlich Excellence" 
          including the Main-Conference, PK/PD-General Concepts Workshop (on Tuesday), 
          Pre-Conference-ISAP-Workshop (on Wednesday), the gala evening, accommodation 
          for 6 nights (September 06-11, 2004, hotel category C or D) for 700 
          EUR.
 
        -  A "Week of Ehrlich Excellence" with registration 
          after June 01, 2004, fee will be 900 EUR.
 
        -  For registration before June 01, 2004, the fee will 
          be 150 EUR for the conference (Thursday 01:30 PM - Saturday 04:00 PM).
 
        -  For registration after June 01, 2004, the fee will 
          be 200 EUR for the conference (Thursday 01:30 PM - Saturday 04:00 PM).
 
        - 100 EUR for each pre-conference workshop (per day) 
          for registrations before June 01, 2004.
 
        - 150 EUR for each pre-conference workshop (per day) 
          for registrations after June 01, 2004.
 
        -  Special fees for students, residents and trainee 
          physicians or colleagues from eastern Europe. 
 
        -  Special fees for colleagues from the developing world 
          on request.
 
         
       
      See 
        details 
       
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