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Thursday - Saturday    September 9-11, 2004; World Conference-Program

 

 

Thursday            September 9, 2004

 

 

 

02:00 PM            Session 1: The basis of antiinfective treatment

 

 

02:00 PM          Pharmacokinetics and tissue penetration of antiinfectives

                        O. Cars, Uppsala, Sweden

02:20 PM          Extra vs. intracellular penetration of antiinfectives

                        P. Tulkens, Louvain, Belgium

02:40 PM          Microdialysis studies in healthy volunteers and patients

                        M. Müller, Vienna, Austria

03:00 PM          In vitro and in vivo models of infection

                        W.A. Craig, Madison, USA

 

03:20 PM          Summary and discussion by chairmen

 

 

03:30 PM            Coffee Break

 

Sponsors’ booths

Paul-Ehrlich-Exhibition

Ehrlich dye laboratory

 

 

04:00 PM            Session 2: Principles of dosing and methods of individualization

 

 

04:00 PM          Why sex and age are unimportant – a pharmacokinetic perspective

                        N. Holford, Auckland, New Zealand

04:20 PM          Drug monitoring to optimize therapy

                        R. Jelliffe, Los Angeles, USA

04:40 PM          PK/PD Optimization of antiinfectives by adaptive feedback control

                        A. Forrest, Buffalo, USA

05:00 PM          Population PK and Monte Carlo Simulation

                        G.L. Drusano, Albany, USA

 

05:20 PM          Summary and discussion by chairmen

 

 

05:30 PM            End of presentations on Thursday

 

 

06:00 PM            Opening Ceremony at the Althoff - Frerich Hall

 

 

07:45 PM            Reception at the Ehrlich Plaza


Friday                September 10, 2004

 

07:00 AM            Registration

 

Sponsors’ booths

Paul-Ehrlich-Exhibition

Ehrlich dye laboratory

 

 

08:00 AM            Session 3: Antiinfectives’ drug development and regulatory processes

 

 

08:00 AM          Guidelines of FDA and EMEA for clinical studies

                        H. Kemmler, Bern, Switzerland

08:20 AM          Predicting drug interactions

                        L.Z. Benet, San Francisco, USA

08:40 AM          Adverse events and antiinfectives’ drug interactions –
lessons of the last 20 years

                        R. Stahlmann, Berlin, Germany

 

09:00 AM          Summary and discussion by chairmen

 

 

09:10 AM            Coffee break

 

Sponsors’ booths

Paul-Ehrlich-Exhibition

Ehrlich dye laboratory

 

 

09:30 AM            Session 4: Antifungals and antivirals

 

 

09:30 AM          Antifungals

                        A. Louie, Albany, USA

09:55 AM          Antivirals

                        G.L. Drusano, Albany, USA

 

10:20 AM          Summary and discussion by chairmen

 

 


Friday                September 10, 2004

 

 

02:05 PM            Session 5: Special populations and clinical pharmacodynamics

 

 

02:05 PM          Dosing issues in neonates and children

                        J.N. v. d. Anker, Washington, USA

02:25 PM          Dosing of antiinfectives in special populations

                        H. Derendorf, Gainesville, USA

02:45 PM          Dosing guidelines in patients with renal replacement

                        F. Thalhammer, Vienna, Austria

03:05 PM          Summary and discussion by chairmen

 

 

03:20 PM            Session 6: Treatment of infection according to site of infection

 

 

03:20 PM          Dosing of antibiotics in skin and soft tissue infections

                        W. Graninger, Vienna, Austria

03:40 PM          Dosing of antibiotics in urinary tract infections

                        K.G. Naber, Straubing, Germany

04:00 PM          Dosing of antibiotics in respiratory tract infections

                        H. Lode, Berlin, Germany

04:25 PM          Sepsis and other difficult conditions

                        T. Welte, Hannover, Germany

 

04:45 PM          Summary and discussion by chairmen

 

 

05:00 PM            End of presentations on Friday

 

 

07:00 PM            Ceremonial Gala Evening to celebrate Paul Ehrlich’s 150th Birthday

(ends 11:30 PM)


Saturday            September 11, 2004

 

 

07:00 AM            Registration

 

Sponsors’ booths

Paul-Ehrlich-Exhibition

Ehrlich dye laboratory

 

 

08:30 AM            Session 7: Dosing of antiinfectives

 

 

08:30 AM          Hepatitis C – dosing regimens

                        S. Rossol, Rüsselsheim, Germany

08:50 AM          Anti-tuberculosis treatment

                        R.S. Wallis, Newark, USA

09:10 AM          Preventing antimalarial resistance

                        N. White, Bangkok, Thailand

09:30 AM          Treatment and dosing of Helicobacter pylori infection –

                        when pharmacology meets clinic

                        P. Malfertheiner, Magdeburg, Germany

09:50 AM          Summary and discussion by chairmen

 

 

10:00 AM            Coffee break

 

Paul-Ehrlich-Exhibition

Colors and art – artists use Ehrlich’s colors

Ehrlich dye laboratory

 

 

10:15 AM            Session 8: Views in PK/PD and controversies

 

 

10:15 AM          Vancomycin – Clinical pharmacodynamics in hospitalized patients

                        J.J. Schentag, Buffalo, USA

10:35 AM          Protein binding – a microbiologist’s view

                        B. Wiedemann, Bonn, Germany

10:50 AM          Protein binding – a pharmacologist’s view

                        H. Derendorf, Gainesville, Florida

11:05 AM          Can resistance be prevented?

                        P.C. Appelbaum, Hershey, USA

11:25 AM          Can resistance be prevented? / Intermittent vs continuous infusion –

                        ISAP position

                        J.W. Mouton, Nijmegen, Netherlands

11:50 AM          Effectiveness of antiinfectives: do not forget the patient!

                        J.C. Pechère, Geneva, Switzerland

12:05 PM          Summary and discussion by chairmen


Saturday            September 11, 2004

 

 

01:30 PM            “Magic Bullets” – Tools and perspectives

 

 

01:30 PM          Pharmacokinetics and pharmacodynamics –
concepts in drug development from Ehrlich to modern PK/PD

                        L.Z. Benet, San Francisco, USA

02:00 PM          The role of animal experimentation in designing
antiinfective therapy from Ehrlich to today’s methods

                        W.A. Craig, Madison, USA

02:30 PM          The challenges of advancing Paul Ehrlich's
chemotherapeutic principles in the present era

                        R.C. Moellering, Boston, USA

03:00 PM          Ehrlich’s modern dream – therapeutic antibodies

                        B. Groner, Frankfurt/M, Germany

 

 

03:30 PM            End of WCDA: Closing remarks

                        K.G. Naber, Straubing, Germany